Because Acthar can be a self-injection, you have the flexibility to administer it whenever and wherever is right for you, per your doctor’s prescription. You can give yourself the injection or ask a care partner for assistance. Your doctor will give you instructions about when and how to take Acthar injections for multiple sclerosis (MS) attacks.

Step-by-step injection training

Watch the videos below for instructions for injecting Acthar subcutaneously or intramuscularly. You can also download our Guide to Taking Acthar.


Before injecting Acthar, remember:

  • Refrigerate Acthar as soon as you receive it and after every use, checking that your refrigerator is set between 36°F and 46°F or 2°C and 8°C
  • Acthar can be administered subcutaneously (beneath the skin) or intramuscularly (into a muscle). Your doctor will advise you about how to inject Acthar and the personalized dose to use
  • Never inject Acthar directly into a vein, and always take Acthar as prescribed by your doctor
  • Please refer to the Important Safety Information about Acthar
  • Talk to your doctor about the potential side effects associated with Acthar, including possible injection-site reactions

Subcutaneous injection training

Step-by-step instructions on how to inject Acthar subcutaneously (beneath the skin).


Intramuscular injection training

Step-by-step instructions on how to inject Acthar intramuscularly (into a muscle).

  • Never inject Acthar directly into a vein
  • Always inject Acthar beneath the skin or into a muscle
  • Follow your doctor’s instructions for injecting Acthar
  • Never stop treatment suddenly unless your doctor tells you to do so
  • Try not to miss any scheduled doctor’s appointments. It is important for your doctor to monitor you while taking Acthar

If you’ve been prescribed Acthar, you have access to a variety of support resources and information.